Pathological Study On Experimental Infection With Mycoplasma Mycoides Subspecies Capri In Different Age Groups of Goats

Authors

  • Ayaz Hussain Panhwar Department of Veterinary Pathology, Faculty of Animal Husbandry & Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan
  • Mansoor Tariq Department of Veterinary Pathology, Facult of Animal Husbandry & Veterinary Sciences, Sindh Agriculture University Tandojam
  • Amjad Ali Channa Department of Veterinary Pathology, Faculty of Animal Husbandry & Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan
  • Zaheer Ahmed Nizamani Department of Veterinary Pathology, Faculty of Animal Husbandry & Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan
  • Ayaz Hussain Mangi Livestock & Fisheries Department, Government of Sindh
  • Riaz Ahmed Leghari Department of Veterinary Medicine, Faculty of Animal Husbandry & Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan
  • Ghulam Mustafa Solangi Department of Veterinary Pathology, Faculty of Animal Husbandry & Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan
  • Shahrood Ahmed Siddiqui Livestock & Fisheries Department, Government of Sindh

DOI:

https://doi.org/10.46568/bios.v4i4.162

Keywords:

Mycoplasma mycoides, antibody titers, cELISA

Abstract

Introduction: To determine clinico-pathology caused by Mycoplasma mycoides subspecies capri (PG3) in goats of different age groups and antibody titers. Methods: Twenty-one goats of three age groups viz; 1, 2 and 3 years with 7 goats of each age. Goats were divided in four groups i-e; G1, G2, G3 each contain 5 goats of each age while G4 comprise 6 goats; 2 from each group. Goats in G1, G2 and G3 were infected with Mycoplasma mycoides (PG3) dose (1×107 CFU/ml/kg) whereas, G4 was kept as control. Clinical examinations were recorded at 12-h intervals. The blood samples collected were tested through cELISA and the specimen of trachea, lungs, kidney, and liver were collected at the end of experiment for gross and histopathology. Results: Temperature, respiratory rate, pulse rate nasal discharge, coughing and lacrimation were noted higher in G1 compared to G2 and G3 groups. Gross pathology showed severe multifocal and diffused necrosis G1 compared to G2 and G3 groups. Histopathology showed sloughing of tracheal mucosa in all groups while hypertrophic secretary glands in G1. Lungs showed emphysema in all groups except G4. Kidneys showed glomerulonephritis while Liver showed congestion and hyperemia in all groups. cELISA, revealed the antibody titers rose from 1st to 3rd week post infection afterwards, reduced slowly. Antibody titers were higher in G1 compared to G2 and G3 groups. Conclusion: Mycoplasma mycoides subspecies capri (PG3) can cause infection in goats of all ages, yet the infection is more severe in young animals compared to old.

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Published

2023-10-10

How to Cite

Ayaz Hussain Panhwar, Mansoor Tariq, Amjad Ali Channa, Zaheer Ahmed Nizamani, Ayaz Hussain Mangi, Riaz Ahmed Leghari, … Shahrood Ahmed Siddiqui. (2023). Pathological Study On Experimental Infection With Mycoplasma Mycoides Subspecies Capri In Different Age Groups of Goats. BioSight, 4(4), 41–50. https://doi.org/10.46568/bios.v4i4.162

Issue

Vol. 4 No. 4 (2023): October

Section

Original Article

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