Bacteriological profile and antimicrobial susceptibility patterns of symptomatic bloodstream infection in Dhaka City

Authors

  • Abedin Zakerin Dept. of Microbiology, School of Biomedical Science, KhwajaYunus Ali University, Bangladesh
  • Md. SifatUz Zaman Dept. of Microbiology, Popular Diagnostic Centre, Dhaka, Bangladesh
  • Fayez Ahmed Dept. of Microbiology, Popular Diagnostic Centre, Dhaka, Bangladesh
  • Farida Yeasmin Faculty of Basic Medical and Pharmaceutical Science, University of Science and Technology Chittagong
  • Md. Babul Aktar Dept. of Microbiology, School of Biomedical Science, KhwajaYunus Ali University, Bangladesh
  • Rasheda Yasmin Shilpi Laboratory of Microbiology, Department of Botany, Jahangirnagar University, Savar, Bangladesh
  • Abdullah Akhtar Ahmed Dept. of Microbiology, School of Biomedical Science, KhwajaYunus Ali University, Bangladesh

DOI:

https://doi.org/10.46568/bios.v2i1.25

Keywords:

Bacterial isolates, bloodstream infection (BSI), Septicemia, antibiotic sensitive and resistance patterns

Abstract

INTRODUCTION: Bacteremia, is regarded as a significant reason in all over the world for morbidity and mortality in mainly sick patients. Invasion by microorganisms in blood constitutes the critical issues in infectious disease. The aims and objectives are to find out the pathogenic agents infecting males and females in blood of different age groups and naturally used antimicrobial sensitivity profiles. METHODS: All the blood samples were collected aseptically and tested in Popular Diagnostic Centre, Dhaka, Bangladesh between May, 2020 and October, 2020. Total 305 blood specimens from both sexes of different age groups were collected. Cultural analysis was performed by Gram staining, phenotypic examination, biochemical and serological analysis. Finally, antibiotic susceptibility test was done against commonly used antibiotics. RESULTS: 96 (31.47%) samples yielded a positive culture with predominant isolate being Salmonella typhi (41.66%)  though Salmonella spp., Salmonella typhi, Staphylococcus spp and Pseudomonas spp. were also detected. Like most of previous reports, Salmonella spp was predominant, this corroborates this study. But the profile of antimicrobial susceptibility of the detected organisms varied comparing studies which were done in the past. The isolates were found mostly resistant to nalidixic acid. Most of the pathogens showed tremendous susceptibility against ceftriaxone, cefixime, ceftazidime etc.

CONCLUSION: The antibiotic selection for the treatment of bacteraemia in patients should always be serious concern due to multidrug resistant (MRD) bacterial isolates. For proper treatment of anti-bacterial resistance and critical mortality and morbidity should be related with the sickness. For validating more reliability, this research requires further work.

References

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Published

2021-06-30

How to Cite

Zakerin, A., Md. SifatUz Zaman, Fayez Ahmed, Farida Yeasmin, Md. Babul Aktar, Rasheda Yasmin Shilpi, & Abdullah Akhtar Ahmed. (2021). Bacteriological profile and antimicrobial susceptibility patterns of symptomatic bloodstream infection in Dhaka City. BioSight, 2(1), 13–17. https://doi.org/10.46568/bios.v2i1.25

Issue

Vol. 2 No. 1 (2021): January-June

Section

Original Article

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