Comparative Analysis of Sensory and Motor Diagnostic Tests for Carpal Tunnel Syndrome: A Regional Perspective

Authors

  • Kawish Arif Department of Physiology, University of Karachi, Karachi, 75270, Pakistan
  • Qurat ul ain Department of Physiology, University of Karachi, Karachi, 75270, Pakistan
  • Mudassir Haider Rizvi Department of Physiology, University of Karachi, Karachi, 75270, Pakistan.
  • Arifa Savanur Department of Physiology, University of Karachi, Karachi, 75270, Pakistan.

DOI:

https://doi.org/10.67773/bios.v7i2.244

Keywords:

Nerve Conduction Studies, Sensory Nerves, Motor Nerves, Median Nerve,, Occupational Neuropathy, Regional Diagnostics, carpel tunnel syndrom

Abstract

Carpal Tunnel Syndrome (CTS) is the most common entrapment neuropathy and a significant cause of occupational disability. Nerve conduction studies (NCS) are widely used for diagnosis, yet regional data from underserved populations remain limited. This was a cross-sectional observational study conducted at the Neuromuscular Physiology Unit, CMH Gilgit. Fifty clinically diagnosed female CTS patients underwent bilateral median and ulnar sensory and motor nerve conduction studies. Parameters evaluated included sensory latency, sensory amplitude, sensory conduction velocity, distal motor latency, proximal motor latency, motor amplitude, and motor conduction velocity. Data were analyzed using SPSS version 22.0. Sensory studies demonstrated prolonged sensory latencies and reduced conduction velocities with increasing symptom severity. Motor studies showed prolonged distal and proximal motor latencies and reduced amplitudes in moderate-to-severe CTS. Greater neurophysiological impairment was observed in dominant hands compared with non-dominant hands. Motor parameters correlated more strongly with functional impairment than sensory parameters. Combined sensory and motor nerve conduction studies provide valuable information for CTS diagnosis and severity assessment. The findings highlight the importance of comprehensive electrodiagnostic evaluation and support the development of region-specific diagnostic reference values. Further studies with larger and more diverse populations are recommended.

References

1. Robbins H. Anatomical study of the median nerve in the carpal tunnel and etiologies of the carpal-tunnel syndrome. J Bone Joint Surg Am. 1963;45:953-66.

2. Ebner P, Kuschner S. Carpal tunnel syndrome and trigger finger: sometimes related. Open Orthop J. 2023;17:e18743250261768. doi:10.2174/0118743250261768231127111757.

3. Simcox T, Seo L, Dunham K, Huang S, Petchprapa C, Wollstein R. Palmar musculature: does it affect the development of carpal tunnel syndrome? A pilot study. J Wrist Surg. 2021;10(3):196-200. doi:10.1055/s-0040-1721437.

4. Sonohata M, Tsuruta T, Mine H, Morimoto T, Mawatari M. The relationship between neuropathic pain and the function of the upper limbs based on clinical severity according to electrophysiological studies in patients with carpal tunnel syndrome. Open Orthop J. 2013;7:99-104. doi:10.2174/1874325001307010099.

5. Presazzi A, Bortolotto C, Zacchino M, Madonia L, Draghi F. Carpal tunnel: normal anatomy, anatomical variants and ultrasound technique. J Ultrasound. 2011;14:40-46. doi:10.1016/j.jus.2011.01.006.

6. Joshi A, Patel K, Mohamed A, Oak S, Zhang MH, Hsiung H, et al. Carpal tunnel syndrome: pathophysiology and comprehensive guidelines for clinical evaluation and treatment. Cureus. 2022;14(7):e27053. doi:10.7759/cureus.27053.

7. American Association of Electrodiagnostic Medicine, American Academy of Neurology, American Academy of Physical Medicine and Rehabilitation. Practice parameter for electrodiagnostic studies in carpal tunnel syndrome: summary statement. Muscle Nerve. 2002;25(6):918-22. doi:10.1002/mus.10185.

8. Chang MH, Liao YC, Lee YC, Hsieh PF, Liu LH. Electrodiagnosis of carpal tunnel syndrome: which transcarpal conduction technique is best? J Clin Neurophysiol. 2009;26(5):366-71. doi:10.1097/WNP.0b013e3181baaafe.

9. Werner RA, Franzblau A. Hand dominance effect on median and ulnar sensory evoked amplitude and latency in asymptomatic workers. Arch Phys Med Rehabil. 1996;77(5):473-76. doi:10.1016/S0003-9993(96)90036-2.

10. Padua L, Coraci D, Erra C, Pazzaglia C, Paolasso I, Loreti C, et al. Carpal tunnel syndrome: clinical features, diagnosis, and management. Lancet Neurol. 2016;15(12):1273-84. doi:10.1016/S1474-4422(16)30231-9.

11. Dabbagh A, MacDermid JC, Yong J, Packham TL, Macedo LG, Ghodrati M. Diagnostic accuracy of sensory and motor tests for the diagnosis of carpal tunnel syndrome: a systematic review. BMC Musculoskelet Disord. 2021;22(1):337. doi:10.1186/s12891-021-04202-y.

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Published

2026-07-15

How to Cite

Arif, K., Qurat ul ain, Haider Rizvi, M., & Savanur, A. (2026). Comparative Analysis of Sensory and Motor Diagnostic Tests for Carpal Tunnel Syndrome: A Regional Perspective. BioSight, 7(2), 1–6. https://doi.org/10.67773/bios.v7i2.244

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Original Article

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